NCF1C

Across TCGA pan-cancer cohorts, NCF1C RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of NCF1C’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NCF1C RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NCF1C is over-expressed in tumor, although a few such as COAD and LUAD show the opposite, repressed pattern.

KIRC, COAD, and KIRP are the cancer types where NCF1C tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NCF1C RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+1.610	<.001	11	view →
COAD	Male	All	−1.101	<.001	11	view →
KIRP	Male	All	+1.379	<.001	9	view →
LUAD	Male	All	−1.082	<.001	8	view →
LUSC	Female	All	−1.312	<.001	7	view →
BLCA	All	III,IV	−0.875	.006	4	view →
STAD	All	All	+0.841	.015	4	view →
HNSC	All	All	+0.357	.021	2	view →
ESCA	All	All	+0.954	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

NCF1C–KIRC

Open the KIRC breakdown →