NCF1B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NCF1B mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCF1B-associated genes across cancer lineages are RN7SL248P, RNU6-87P, and RN7SL301P. Each is linked with NCF1B in more than 1 cancer types. Because this analysis shows association rather than direction, both NCF1B-to-partner and partner-to-NCF1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by NCF1B-low versus NCF1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCF1B→partner) and Y-score (partner→NCF1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.116+4.400<.001.00632
UCECRNU6-87P →+0.625+3.046.007.00831
UCECRN7SL301P →+0.210+3.639.002.00231
UCECRNA5SP440 →+0.810+3.179<.001.00631
SKCMLINC01673 →+0.950+4.410<.001.00631
SKCMNDUFB11P1 →+0.127+4.500<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

RN7SL248P by NCF1B expression — UCEC

Box plot of RN7SL248P in NCF1B-low vs NCF1B-high samples in UCEC.

Explore this box plot interactively →

Exploration