NCF1B

Across TCGA pan-cancer cohorts, NCF1B RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of NCF1B’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NCF1B RNA is repressed in tumor relative to normal tissue. In most cancer types NCF1B is over-expressed in tumor, although a few such as COAD and LUSC show the opposite, repressed pattern.

COAD, KIRC, and LUSC are the cancer types where NCF1B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NCF1B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	III,IV	−1.092	<.001	12	view →
KIRC	Female	All	+1.202	<.001	11	view →
LUSC	Female	All	−1.255	<.001	8	view →
KIRP	Male	All	+1.008	<.001	8	view →
LUAD	Male	All	−0.907	<.001	8	view →
BLCA	All	III,IV	−0.693	.003	6	view →
PAAD	Male	All	−0.480	.005	2	view →
HNSC	Female	All	+0.389	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

NCF1B–COAD

Open the COAD breakdown →