NCALD

Across TCGA patient cohorts, NCALD mutation is significantly associated with the RNA expression of many other genes, with 1,431 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCALD-associated genes across cancer lineages are OR8B6P, SNRPGP7, and NIPA2P4. Each is linked with NCALD in more than 1 cancer types. Because this analysis shows association rather than direction, both NCALD-to-partner and partner-to-NCALD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B6P grouped by NCALD-low versus NCALD-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCALD→partner) and Y-score (partner→NCALD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR8B6P →	+0.058	+5.594	<.001	.004	3	2
UCEC	SNRPGP7 →	+0.141	+2.833	<.001	.009	3	2
UCEC	NIPA2P4 →	+0.047	+2.300	.004	.001	3	2
SKCM	DNM1P28 →	+0.101	+5.224	<.001	.007	3	1
SKCM	MIR4480 →	+0.607	+6.469	<.001	.001	3	1
SKCM	RN7SL690P →	+0.193	+5.771	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,431 associations by consensus.

OR8B6P by NCALD expression — SKCM

Explore this box plot interactively →