NBPF20

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NBPF20 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NBPF20-associated genes across cancer lineages are RN7SL598P, MRPS21P5, and TOMM22P3. Each is linked with NBPF20 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF20-to-partner and partner-to-NBPF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL598P grouped by NBPF20-low versus NBPF20-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF20→partner) and Y-score (partner→NBPF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRN7SL598P →+0.507+5.516<.001.00432
COADMRPS21P5 →+0.463+5.893<.001.00231
COADTOMM22P3 →+0.239+5.435<.001.00531
COADC11orf98P1 →+0.491+5.435<.001.00531
COADBRWD1P3 →+0.210+5.693.008.00331
COADIGHD4-4 →+2.096+5.357<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

RN7SL598P by NBPF20 expression — COAD

Box plot of RN7SL598P in NBPF20-low vs NBPF20-high samples in COAD.

Explore this box plot interactively →

Exploration