NBPF20

Across TCGA pan-cancer cohorts, NBPF20 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of NBPF20’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NBPF20 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NBPF20 is over-expressed in tumor, although a few such as PAAD and KICH show the opposite, repressed pattern.

HNSC, KIRC, and STAD are the cancer types where NBPF20 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NBPF20 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.236	<.001	12	view →
KIRC	Female	All	+0.140	<.001	11	view →
STAD	All	IV	+0.216	<.001	9	view →
KIRP	All	All	+0.140	<.001	9	view →
COAD	Male	All	+0.130	<.001	8	view →
BLCA	All	All	+0.157	<.001	6	view →
LIHC	All	All	+0.134	.004	5	view →
BRCA	All	II,III,IV	+0.152	<.001	4	view →
READ	All	All	+0.132	.032	4	view →
CHOL	All	All	+0.321	.001	3	view →
LUSC	Male	All	+0.124	<.001	3	view →
PRAD	All	All	+0.188	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

NBPF20–HNSC

Open the HNSC breakdown →