NBPF10

Across TCGA patient cohorts, NBPF10 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF10-associated genes across cancer lineages are RNA5SP161, MIR4727, and ZSWIM5P1. Each is linked with NBPF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF10-to-partner and partner-to-NBPF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP161 grouped by NBPF10-low versus NBPF10-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF10→partner) and Y-score (partner→NBPF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP161 →	+0.485	+6.342	<.001	.001	3	2
LUSC	MIR4727 →	+0.791	+5.404	<.001	.005	3	2
CESC	ZSWIM5P1 →	+0.021	+5.306	<.001	.006	3	1
CESC	TRIM67-AS1 →	+0.074	+5.539	<.001	.004	3	1
CESC	RN7SL492P →	+0.141	+5.669	.002	.003	3	1
CESC	H4P1 →	+0.214	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

RNA5SP161 by NBPF10 expression — CESC

Explore this box plot interactively →