NBPF10

Across TCGA pan-cancer cohorts, NBPF10 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of NBPF10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NBPF10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NBPF10 is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.

KIRC, UCEC, and THCA are the cancer types where NBPF10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NBPF10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+0.146	<.001	9	view →
UCEC	All	All	−0.265	<.001	6	view →
THCA	Female	All	−0.212	<.001	5	view →
LIHC	All	All	+0.138	<.001	5	view →
KIRP	All	All	+0.137	.002	4	view →
CHOL	Female	All	+0.760	<.001	3	view →
KICH	All	All	−0.165	.003	2	view →
LUSC	Male	All	−0.098	.018	1	view →
COAD	All	All	−0.058	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

NBPF10–KIRC

Open the KIRC breakdown →