NBPF10

Across TCGA pan-cancer cohorts, NBPF10 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated NBPF10 data layer compared with 3 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher NBPF10 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NBPF10 expression acts as an unfavorable survival marker, although some lineages such as UCS and ESCA show a favorable association.

ACC, OV, and COAD are the cancer types where NBPF10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.504	0.802	<.001	78	view →
OV	OS	Tertile	All	0.270	0.422	<.001	64	view →
COAD	OS	Quartile	III,IV	0.259	0.860	<.001	63	view →
UVM	OS	Median	All	0.482	0.853	.007	25	view →
UCS	DFS	Tertile	IV	0.932	0.361	.024	24	view →
DLBC	DFS	Quartile	All	0.344	1.000	.011	19	view →
LUAD	DFS	Median	IV	0.256	0.729	.006	19	view →
LGG	DFS	Tertile	All	0.786	0.886	.002	16	view →
MESO	DFS	Tertile	IV	0.191	0.535	.013	15	view →
KICH	OS	Median	All	0.668	0.961	.010	14	view →
ESCA	OS	Tertile	III,IV	0.678	0.348	.007	13	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

NBPF10–ACC (DFS)

Open the ACC breakdown →