NBPF10

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NBPF10 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. CESC shows the largest number of these associations.

The most reproducible NBPF10-associated genes across cancer lineages are CD8+ T-cells, CD8+ Tcm, and CD4+ naive T-cells. Each is linked with NBPF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF10-to-partner and partner-to-NBPF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by NBPF10-low versus NBPF10-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF10→partner) and Y-score (partner→NBPF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCCD8+ T-cells →+0.061+4.760.001.01231
CESCCD8+ Tcm →+0.085+3.918.010.03631
CESCCD4+ naive T-cells →+0.025+5.969<.001.00231
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ T-cells by NBPF10 expression — CESC

Box plot of CD8+ T-cells in NBPF10-low vs NBPF10-high samples in CESC.

Explore this box plot interactively →

Exploration