NBPF10

Across TCGA cell cohorts, NBPF10 mutation is significantly associated with the RNA expression of many other genes, with 357 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NBPF10-associated genes across cancer lineages are MTNR1B, MYH1, and DEFB126. Each is linked with NBPF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF10-to-partner and partner-to-NBPF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTNR1B grouped by NBPF10-low versus NBPF10-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF10→partner) and Y-score (partner→NBPF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MTNR1B →	+0.075	+4.786	<.001	.001	3	2
BLOOD_Lymphoma	MYH1 →	+0.045	+4.350	<.001	.005	3	2
BLOOD_Lymphoma	DEFB126 →	+0.530	+4.714	<.001	.002	3	2
BLOOD_Lymphoma	OR8G5 →	+0.636	+4.927	<.001	.001	3	2
BLOOD_Lymphoma	MYH13 →	+0.023	+4.191	.003	.007	3	2
OVARY	HTR3C →	+0.073	+3.263	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 357 associations by consensus.

MTNR1B by NBPF10 expression — PANCREAS

Explore this box plot interactively →