Across TCGA patient cohorts, NAT8L RNA expression is significantly associated with the protein abundance of many other proteins, with 15,827 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NAT8L-associated proteins across cancer lineages are MSI1, KIF1A_S937, and PRKAR2B. Each is linked with NAT8L in more than 5 cancer types. Because this analysis shows association rather than direction, both NAT8L-to-partner and partner-to-NAT8L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT8L→partner) and Y-score (partner→NAT8L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MSI1 →	+0.892	+0.473	.002	.004	3	6
LSCC	KIF1A_S937 →	+2.701	+0.777	<.001	<.001	3	5
GBM	PRKAR2B →	+0.672	+0.708	<.001	.002	2	5
UCEC	ARFIP1 →	-0.381	-1.210	<.001	<.001	3	4
GBM	PARP4 →	-0.383	-0.654	<.001	<.001	3	4
LSCC	TUBB4A →	+0.908	+0.553	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,827 associations by consensus.

Exploration

NAT8L survival (RNA) · tumor vs normal (RNA) · all NAT8L data types