NASP

Across TCGA patient cohorts, NASP protein abundance is significantly associated with the RNA expression of many other genes, with 17,017 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NASP-associated genes across cancer lineages are SMC2, SASS6, and MCM7. Each is linked with NASP in more than 9 cancer types. Because this analysis shows association rather than direction, both NASP-to-partner and partner-to-NASP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NASP versus SMC2 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NASP→partner) and Y-score (partner→NASP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SMC2 →	+0.931	+0.589	<.001	<.001	3	10
LSCC	SASS6 →	+0.862	+0.708	<.001	<.001	3	10
HNSC	MCM7 →	+0.996	+0.291	<.001	<.001	3	10
HNSC	PPIH →	+0.563	+0.419	<.001	<.001	3	10
GBM	WDHD1 →	+0.840	+0.595	<.001	<.001	3	10
LSCC	MSH2 →	+0.789	+0.478	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,017 associations by consensus.

NASP vs SMC2 — OV

Explore this scatter interactively →