NADK

Across TCGA patient cohorts, NADK mutation is significantly associated with the RNA expression of many other genes, with 1,643 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NADK-associated genes across cancer lineages are RNU6-693P, MIR190A, and RN7SL26P. Each is linked with NADK in more than 2 cancer types. Because this analysis shows association rather than direction, both NADK-to-partner and partner-to-NADK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-693P grouped by NADK-low versus NADK-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NADK→partner) and Y-score (partner→NADK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-693P →	+0.235	+3.569	<.001	.004	3	3
COAD	MIR190A →	+0.235	+4.595	<.001	.004	3	2
CESC	RN7SL26P →	+0.112	+3.612	.002	.001	3	2
UCEC	TMEM250 →	+0.330	+2.823	.009	.001	3	2
UCEC	RNU6-835P →	+0.096	+4.019	<.001	.005	3	2
SKCM	DEFB103A →	+0.029	+3.993	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,643 associations by consensus.

RNU6-693P by NADK expression — CESC

Explore this box plot interactively →