NAB1

Across TCGA patient cohorts, NAB1 mutation is significantly associated with the RNA expression of many other genes, with 1,840 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAB1-associated genes across cancer lineages are MIR6796, MESTP2, and MIR649. Each is linked with NAB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAB1-to-partner and partner-to-NAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6796 grouped by NAB1-low versus NAB1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAB1→partner) and Y-score (partner→NAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR6796 →	+0.624	+5.268	<.001	.006	3	2
BLCA	MESTP2 →	+0.047	+4.788	<.001	.006	3	2
COAD	MIR649 →	+0.604	+4.435	<.001	.001	3	2
LIHC	RNU7-11P →	+0.625	+5.355	<.001	.005	3	2
CESC	DDX11L1 →	+0.034	+4.413	<.001	.002	3	2
UCEC	RNU6-879P →	+0.344	+1.944	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,840 associations by consensus.

MIR6796 by NAB1 expression — LIHC

Explore this box plot interactively →