NAA16

Across TCGA cell cohorts, NAA16 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAA16-associated genes across cancer lineages are FGF23, VAX1, and GP9. Each is linked with NAA16 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA16-to-partner and partner-to-NAA16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGF23 grouped by NAA16-low versus NAA16-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA16→partner) and Y-score (partner→NAA16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FGF23 →	+0.540	+3.584	<.001	.003	3	1
LARGE_INTESTINE	VAX1 →	+0.541	+3.285	.004	.007	3	1
LARGE_INTESTINE	GP9 →	+0.057	+2.933	.009	.003	3	1
LARGE_INTESTINE	OR10W1 →	+0.012	+3.240	<.001	.004	3	1
LARGE_INTESTINE	OR4F21 →	+0.138	+3.141	<.001	.002	3	1
LARGE_INTESTINE	TAFA1 →	+0.206	+3.425	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

FGF23 by NAA16 expression — LARGE_INTESTINE

Explore this box plot interactively →