MZT2B

Across TCGA cell cohorts, MZT2B mutation is significantly associated with the mutation status of many other genes, with 120 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MZT2B-associated genes across cancer lineages are GNAT3, SCRT1, and ACOT8. Each is linked with MZT2B in more than 1 cancer types. Because this analysis shows association rather than direction, both MZT2B-to-partner and partner-to-MZT2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNAT3 grouped by MZT2B-low versus MZT2B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MZT2B→partner) and Y-score (partner→MZT2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GNAT3 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	SCRT1 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	ACOT8 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	KLF9 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	SLC17A3 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	SNAI2 →	+4.523	+5.087	.006	.006	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 120 associations by consensus.

GNAT3 by MZT2B expression — LARGE_INTESTINE

Explore this box plot interactively →