MYO7B

Across TCGA patient cohorts, MYO7B mutation is significantly associated with the total protein of many other genes, with 77 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO7B-associated genes across cancer lineages are Caspase-7-cleavedD198, FASN, and ASNS. Each is linked with MYO7B in more than 4 cancer types. Because this analysis shows association rather than direction, both MYO7B-to-partner and partner-to-MYO7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by MYO7B-low versus MYO7B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO7B→partner) and Y-score (partner→MYO7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.982	+3.338	<.001	.004	3	5
BLCA	FASN →	+0.500	+3.584	.029	.002	3	4
COAD	ASNS →	+0.465	+1.493	.001	.035	3	4
UCEC	PDCD4 →	-0.562	-1.621	<.001	<.001	3	4
LUSC	MSH6 →	+0.292	+1.511	.031	.017	3	3
UCEC	p38-MAPK_pT180_Y182 →	-0.329	-1.584	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

Caspase-7-cleavedD198 by MYO7B expression — COAD

Explore this box plot interactively →