MYO7B

Across TCGA cell cohorts, MYO7B mutation is significantly associated with the RNA expression of many other genes, with 691 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYO7B-associated genes across cancer lineages are CCNE2, MAGEB10, and ATG4C. Each is linked with MYO7B in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO7B-to-partner and partner-to-MYO7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNE2 grouped by MYO7B-low versus MYO7B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO7B→partner) and Y-score (partner→MYO7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCNE2 →	+0.805	+3.321	<.001	.003	3	3
SOFT_TISSUE	MAGEB10 →	+0.673	+4.222	<.001	.007	3	2
STOMACH	ATG4C →	+0.545	+3.240	<.001	.003	3	2
STOMACH	TMEM241 →	+0.685	+3.240	.005	.003	2	3
STOMACH	COX15 →	+0.543	+3.240	.005	.003	3	2
LARGE_INTESTINE	ZMYND8 →	-0.611	-2.000	.009	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 691 associations by consensus.

CCNE2 by MYO7B expression — LARGE_INTESTINE

Explore this box plot interactively →