MYL12B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYL12B protein abundance is significantly associated with the RNA expression of many other genes, with 6,574 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MYL12B-associated genes across cancer lineages are COX20P2, MYH9, and PLS3. Each is linked with MYL12B in more than 1 cancer types. Because this analysis shows association rather than direction, both MYL12B-to-partner and partner-to-MYL12B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYL12B versus COX20P2 in CCRCC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL12B→partner) and Y-score (partner→MYL12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCCOX20P2 →-0.192-0.251<.001<.00132
LSCCMYH9 →+0.688+0.913<.001.00732
LSCCPLS3 →+1.010+0.625<.001<.00132
LSCCID3 →+1.136+0.680.001.00932
LSCCMACF1 →+0.496+0.503.001.00932
LSCCEHD3 →+0.914+0.966.008.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,574 associations by consensus.

MYL12B vs COX20P2 — CCRCC

Per-sample scatter of MYL12B vs COX20P2 in CCRCC (Pearson r = -0.37).

Explore this scatter interactively →

Exploration