MYL12B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYL12B mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible MYL12B-associated genes across cancer lineages are Monocytes and NK cells. Each is linked with MYL12B in more than 1 cancer types. Because this analysis shows association rather than direction, both MYL12B-to-partner and partner-to-MYL12B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by MYL12B-low versus MYL12B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL12B→partner) and Y-score (partner→MYL12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMonocytes →+0.038+5.618<.001.03931
STADNK cells →+0.011+5.597<.001.04031
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Monocytes by MYL12B expression — BLCA

Box plot of Monocytes in MYL12B-low vs MYL12B-high samples in BLCA.

Explore this box plot interactively →

Exploration