MYL12B

Across TCGA cell cohorts, MYL12B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,969 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MYL12B-associated GO terms across cancer lineages are Negative regulation of macrophage colony-stimulating factor signaling pathway, Regulation of chemotaxis, and Ventricular cardiac muscle cell differentiation. Each is linked with MYL12B in more than 11 cancer types. Because this analysis shows association rather than direction, both MYL12B-to-partner and partner-to-MYL12B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of macrophage colony-stimulating factor signaling pathway grouped by MYL12B-low versus MYL12B-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL12B→partner) and Y-score (partner→MYL12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of macrophage colony-stimulating factor signaling pathway →	+0.150	+0.725	.001	<.001	2	12
BONE	Regulation of chemotaxis →	+0.114	+1.255	<.001	<.001	3	9
STOMACH	Ventricular cardiac muscle cell differentiation →	+0.248	+1.192	.002	.005	2	9
BONE	tRNA transcription by RNA polymerase III →	-0.113	-0.928	.001	<.001	3	8
BONE	Positive regulation of chemotaxis →	+0.124	+0.916	<.001	.001	3	8
SOFT_TISSUE	Neutrophil degranulation →	+0.203	+1.045	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,969 associations by consensus.

Negative regulation of macrophage colony-stimulating factor signaling pathway by MYL12B expression — BREAST

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