MYH7B

Across TCGA patient cohorts, MYH7B mutation is significantly associated with the RNA expression of many other genes, with 4,575 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYH7B-associated genes across cancer lineages are SKA1, MASTL, and KNL1. Each is linked with MYH7B in more than 4 cancer types. Because this analysis shows association rather than direction, both MYH7B-to-partner and partner-to-MYH7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKA1 grouped by MYH7B-low versus MYH7B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH7B→partner) and Y-score (partner→MYH7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SKA1 →	+0.804	+3.727	<.001	<.001	3	5
SKCM	MASTL →	+0.475	+1.604	.002	.001	3	5
SKCM	KNL1 →	+0.458	+1.397	.004	.005	3	5
SKCM	CDCA5 →	+0.461	+2.106	.003	.003	3	5
COAD	WDR76 →	+0.715	+3.726	<.001	<.001	3	5
SKCM	CKAP2L →	+0.548	+1.765	.002	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,575 associations by consensus.

SKA1 by MYH7B expression — COAD

Explore this box plot interactively →