MXRA5

Across TCGA cell cohorts, MXRA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,690 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MXRA5-associated GO terms across cancer lineages are Response to topologically incorrect protein, Positive regulation of protein folding, and Chaperone-mediated autophagy. Each is linked with MXRA5 in more than 7 cancer types. Because this analysis shows association rather than direction, both MXRA5-to-partner and partner-to-MXRA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to topologically incorrect protein grouped by MXRA5-low versus MXRA5-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MXRA5→partner) and Y-score (partner→MXRA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Response to topologically incorrect protein →	+0.089	+1.846	<.001	<.001	3	8
BONE	Positive regulation of protein folding →	+0.209	+1.760	<.001	.007	3	7
BONE	Chaperone-mediated autophagy →	+0.132	+1.428	.003	.009	3	7
BONE	Protein localization to endoplasmic reticulum →	+0.158	+1.908	<.001	.003	3	7
OVARY	Negative regulation of transforming growth factor beta production →	+0.191	+1.489	<.001	.003	3	7
SKIN	Maintenance of protein localization in organelle →	+0.085	+1.250	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,690 associations by consensus.

Response to topologically incorrect protein by MXRA5 expression — SKIN

Explore this box plot interactively →