MXRA5

Across TCGA cell cohorts, MXRA5 mutation is significantly associated with the RNA expression of many other genes, with 1,616 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MXRA5-associated genes across cancer lineages are CUEDC2, FEM1A, and TNFAIP1. Each is linked with MXRA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both MXRA5-to-partner and partner-to-MXRA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CUEDC2 grouped by MXRA5-low versus MXRA5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MXRA5→partner) and Y-score (partner→MXRA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CUEDC2 →	+0.575	+3.584	<.001	<.001	3	3
BLOOD_Leukemia	FEM1A →	+0.547	+3.503	<.001	.001	3	3
BLOOD_Leukemia	TNFAIP1 →	+0.404	+3.594	<.001	.001	3	3
BLOOD_Leukemia	TTC5 →	+0.617	+3.730	<.001	<.001	3	3
BLOOD_Leukemia	SAXO1 →	+0.031	+2.196	<.001	.005	3	3
BLOOD_Leukemia	H2AZ1 →	+0.589	+3.228	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,616 associations by consensus.

CUEDC2 by MXRA5 expression — LARGE_INTESTINE

Explore this box plot interactively →