MVP

Across TCGA cell cohorts, MVP protein abundance is significantly associated with the RNA expression of many other genes, with 7,365 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MVP-associated genes across cancer lineages are SCARB1, DCTN3, and TM7SF3. Each is linked with MVP in more than 10 cancer types. Because this analysis shows association rather than direction, both MVP-to-partner and partner-to-MVP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MVP versus SCARB1 in SOFT_TISSUE, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MVP→partner) and Y-score (partner→MVP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SCARB1 →	+2.163	+2.341	<.001	.001	3	11
SKIN	DCTN3 →	-0.777	-1.954	.002	<.001	3	5
OVARY	TM7SF3 →	-0.924	-1.872	.004	<.001	3	5
BLOOD_Lymphoma	COPG2 →	-0.634	-1.026	.008	<.001	3	5
LIVER	BRD3OS →	-1.375	-1.847	.008	.001	3	4
CNS	GBX1 →	-0.068	-0.969	.004	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,365 associations by consensus.

MVP vs SCARB1 — SOFT_TISSUE

Explore this scatter interactively →