Q-omics provides the consensus-scored MUSTN1 profile across patient tissues and cancer cell-line models. MUSTN1 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, MUSTN1 is differentially expressed in 14, with the highest sampling consensus in BLCA. Additionally, MUSTN1 RNA expression shows 14,945 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, BLCA, and UVM as cancer lineages where MUSTN1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MUSTN1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MUSTN1 survival associations across molecular data types. MUSTN1 RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MUSTN1 RNA expression–survival associations across cancer types. High MUSTN1 expression shows unfavorable associations in ACC, LGG, MESO, OV and KIRC, but favorable associations in BRCA. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for MUSTN1 RNA expression.
This table summarizes MUSTN1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for MUSTN1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MUSTN1 shows lower tumor expression in BLCA, LUAD, HNSC, LUSC and STAD and higher tumor expression in LIHC. The BLCA box plot shows higher MUSTN1 RNA expression in normal versus tumor tissue (log2 FC = −0.756, t-test p < 0.001).
This table shows molecular features associated with MUSTN1 in patient tissues and cancer cell lines. In patient samples, MUSTN1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, MUSTN1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in PANCREAS, while CRISPR and shRNA rows add functional-dependency signals in STOMACH and SOFT_TISSUE.
