MUSTN1

Across TCGA cell cohorts, MUSTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,818 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MUSTN1-associated GO terms across cancer lineages are Cellular response to acidic pH, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with MUSTN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both MUSTN1-to-partner and partner-to-MUSTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to acidic pH grouped by MUSTN1-low versus MUSTN1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MUSTN1→partner) and Y-score (partner→MUSTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cellular response to acidic pH →	-0.184	-0.478	<.001	.003	3	7
SOFT_TISSUE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.107	+2.086	<.001	.003	3	7
SOFT_TISSUE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.080	+1.507	<.001	<.001	3	7
SOFT_TISSUE	DNA topological change →	+0.091	+1.621	<.001	<.001	3	6
SOFT_TISSUE	Response to mechanical stimulus →	-0.050	-1.668	<.001	<.001	3	6
SOFT_TISSUE	Spliceosomal complex assembly →	+0.095	+2.915	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,818 associations by consensus.

Cellular response to acidic pH by MUSTN1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →