MTTP

Across TCGA patient cohorts, MTTP RNA expression is significantly associated with the go_rna of many other GO terms, with 7,161 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible MTTP-associated GO terms across cancer lineages are Autophagy of mitochondrion, Protein localization to nuclear body, and Regulation of DNA biosynthetic process. Each is linked with MTTP in more than 18 cancer types. Because this analysis shows association rather than direction, both MTTP-to-partner and partner-to-MTTP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagy of mitochondrion grouped by MTTP-low versus MTTP-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTTP→partner) and Y-score (partner→MTTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Autophagy of mitochondrion →	+0.063	+0.356	<.001	<.001	3	19
UVM	Protein localization to nuclear body →	+0.058	+0.270	<.001	<.001	3	18
ESCA	Regulation of DNA biosynthetic process →	+0.062	+0.869	<.001	<.001	3	18
THYM	Protein import into peroxisome matrix, receptor recycling →	+0.063	+0.227	<.001	<.001	3	18
UVM	Rescue of stalled ribosome →	+0.086	+0.382	<.001	<.001	3	18
UVM	Response to insulin →	+0.035	+0.398	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

Autophagy of mitochondrion by MTTP expression — UVM

Explore this box plot interactively →