MTTP

Across TCGA cell cohorts, MTTP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,163 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible MTTP-associated GO terms across cancer lineages are Chylomicron assembly, Protein modification by small protein removal, and Endosomal lumen acidification. Each is linked with MTTP in more than 9 cancer types. Because this analysis shows association rather than direction, both MTTP-to-partner and partner-to-MTTP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chylomicron assembly grouped by MTTP-low versus MTTP-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTTP→partner) and Y-score (partner→MTTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Chylomicron assembly →	-0.386	-0.917	<.001	<.001	3	10
SOFT_TISSUE	Protein modification by small protein removal →	+0.058	+0.182	<.001	<.001	3	6
PANCREAS	Endosomal lumen acidification →	+0.084	+0.115	<.001	.005	2	6
BLOOD_Lymphoma	Peptidyl-serine phosphorylation →	+0.050	+0.574	<.001	<.001	3	5
BLOOD_Lymphoma	Peptidyl-serine modification →	+0.051	+0.621	<.001	<.001	3	5
BLOOD_Lymphoma	Protein polyubiquitination →	+0.030	+0.534	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,163 associations by consensus.

Chylomicron assembly by MTTP expression — CNS

Explore this box plot interactively →