MTREX

Across TCGA cell cohorts, MTREX protein abundance is significantly associated with the RNA expression of many other genes, with 3,575 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MTREX-associated genes across cancer lineages are STUB1, LY9, and CCDC62. Each is linked with MTREX in more than 1 cancer types. Because this analysis shows association rather than direction, both MTREX-to-partner and partner-to-MTREX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTREX versus STUB1 in BLOOD_Lymphoma, with a Pearson correlation of -0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTREX→partner) and Y-score (partner→MTREX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	STUB1 →	-0.676	-1.197	<.001	.002	3	1
BLOOD_Lymphoma	LY9 →	+3.043	+1.146	<.001	.002	3	1
BLOOD_Lymphoma	CCDC62 →	-0.347	-0.879	.006	.008	3	1
BLOOD_Lymphoma	NTPCR →	+0.969	+1.481	.009	.004	3	1
BLOOD_Lymphoma	SLC14A1 →	+0.318	+1.146	<.001	.002	3	1
BLOOD_Lymphoma	NR1I3 →	-0.468	-1.106	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,575 associations by consensus.

MTREX vs STUB1 — BLOOD_Lymphoma

Explore this scatter interactively →