MTND5P2

Across TCGA patient cohorts, MTND5P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,427 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTND5P2-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, Positive regulation of DNA metabolic process, and snRNA metabolic process. Each is linked with MTND5P2 in more than 16 cancer types. Because this analysis shows association rather than direction, both MTND5P2-to-partner and partner-to-MTND5P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA metabolic process grouped by MTND5P2-low versus MTND5P2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTND5P2→partner) and Y-score (partner→MTND5P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of mRNA metabolic process →	+0.055	+0.283	<.001	<.001	3	17
STAD	Positive regulation of DNA metabolic process →	+0.044	+0.179	<.001	<.001	3	17
ESCA	snRNA metabolic process →	+0.047	+0.254	<.001	<.001	3	16
ESCA	Regulation of DNA biosynthetic process →	+0.047	+0.280	<.001	<.001	3	16
ESCA	Positive regulation of chromosome organization →	+0.053	+0.306	<.001	<.001	3	16
ESCA	Protein polyubiquitination →	+0.047	+0.253	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,427 associations by consensus.

Negative regulation of mRNA metabolic process by MTND5P2 expression — ESCA

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