MTND4P28

Across TCGA pan-cancer cohorts, MTND4P28 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MTND4P28 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher MTND4P28 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTND4P28 expression acts as an unfavorable survival marker.

KICH, THCA, and READ are the cancer types where MTND4P28 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.362	0.933	<.001	135	view →
THCA	DFS	Tertile	All	0.087	0.868	<.001	54	view →
READ	DFS	Tertile	All	0.082	0.845	<.001	54	view →
LIHC	OS	Tertile	III,IV	0.051	0.650	<.001	54	view →
STAD	OS	Tertile	III,IV	0.338	0.649	.005	36	view →
ESCA	DFS	Tertile	III,IV	0.097	0.456	<.001	18	view →
UCEC	DFS	Tertile	All	0.785	0.900	.016	18	view →
SARC	OS	Tertile	All	0.295	0.776	<.001	18	view →
SKCM	OS	Tertile	III,IV	0.289	0.840	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MTND4P28–KICH (DFS)

Open the KICH breakdown →