MTND4P21

Across TCGA patient cohorts, MTND4P21 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,189 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible MTND4P21-associated GO terms across cancer lineages are Aerobic respiration, Anterograde dendritic transport, and Oxidative phosphorylation. Each is linked with MTND4P21 in more than 5 cancer types. Because this analysis shows association rather than direction, both MTND4P21-to-partner and partner-to-MTND4P21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by MTND4P21-low versus MTND4P21-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTND4P21→partner) and Y-score (partner→MTND4P21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Aerobic respiration →	+0.023	+0.010	<.001	<.001	3	5
ESCA	Anterograde dendritic transport →	+0.050	+0.150	.004	.001	2	6
ESCA	Oxidative phosphorylation →	+0.040	+0.098	.003	<.001	2	5
ESCA	Protein folding →	+0.047	+0.118	<.001	<.001	3	4
ESCA	Protein deacetylation →	+0.044	+0.104	.002	.001	1	6
ESCA	Protein targeting to membrane →	+0.034	+0.097	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,189 associations by consensus.

Aerobic respiration by MTND4P21 expression — HNSC

Explore this box plot interactively →