MTND4LP30

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, MTND4LP30 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MTND4LP30’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MTND4LP30 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTND4LP30 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KICH, KIRC, and KIRP are the cancer types where MTND4LP30 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND4LP30 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHFemaleAll+1.107<.0014view →
KIRCMaleIV−0.585.0193view →
KIRPFemaleII,III,IV−1.014.0142view →
PRADAllAll+0.379.0082view →
LIHCAllAll−0.251.0081view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration