MTND3P23

Across TCGA patient cohorts, MTND3P23 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,373 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTND3P23-associated GO terms across cancer lineages are Negative regulation of epidermal growth factor receptor signaling pathway, Autophagosome organization, and Negative regulation of ERBB signaling pathway. Each is linked with MTND3P23 in more than 22 cancer types. Because this analysis shows association rather than direction, both MTND3P23-to-partner and partner-to-MTND3P23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of epidermal growth factor receptor signaling pathway grouped by MTND3P23-low versus MTND3P23-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTND3P23→partner) and Y-score (partner→MTND3P23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of epidermal growth factor receptor signaling pathway →	+0.056	+0.197	<.001	<.001	3	23
ESCA	Autophagosome organization →	+0.047	+0.170	.001	<.001	3	22
STAD	Negative regulation of ERBB signaling pathway →	+0.044	+0.145	<.001	<.001	3	22
ESCA	Regulation of organelle assembly →	+0.062	+0.235	.003	<.001	3	22
ESCA	Negative regulation of cellular catabolic process →	+0.050	+0.180	.001	<.001	3	21
STAD	Protein acylation →	+0.042	+0.156	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,373 associations by consensus.

Negative regulation of epidermal growth factor receptor signaling pathway by MTND3P23 expression — ESCA

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