MTND3P23

Across TCGA pan-cancer cohorts, MTND3P23 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MTND3P23’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MTND3P23 RNA is repressed in tumor relative to normal tissue. In most cancer types MTND3P23 is over-expressed in tumor, although a few such as THCA and PAAD show the opposite, repressed pattern.

THCA, COAD, and PAAD are the cancer types where MTND3P23 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTND3P23 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.126	<.001	7	view →
COAD	Male	All	+0.137	.019	4	view →
PAAD	Female	All	−0.270	.046	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MTND3P23–THCA

Open the THCA breakdown →