MTND3P23

Across TCGA pan-cancer cohorts, MTND3P23 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MTND3P23 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MTND3P23 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTND3P23 expression acts as an unfavorable survival marker, although some lineages such as SARC and LUAD show a favorable association.

KIRC, LUSC, and THCA are the cancer types where MTND3P23 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.738	0.856	<.001	126	view →
LUSC	DFS	Tertile	III,IV	0.155	0.739	.011	36	view →
THCA	OS	Tertile	II,III,IV	0.871	0.978	<.001	36	view →
SARC	OS	Tertile	All	0.798	0.464	.001	36	view →
LUAD	DFS	Tertile	All	0.738	0.632	.007	31	view →
BRCA	DFS	Tertile	III,IV	0.964	0.838	.012	30	view →
PRAD	DFS	Tertile	All	0.688	0.815	<.001	24	view →
ESCA	DFS	Median	IV	0.634	0.205	.006	18	view →
GBM	OS	Tertile	All	0.322	0.433	.043	18	view →
LIHC	DFS	Tertile	All	0.335	0.592	<.001	18	view →
PAAD	DFS	Quartile	All	0.329	0.517	.010	13	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

MTND3P23–KIRC (OS)

Open the KIRC breakdown →