Q-omics provides the consensus-scored MTCO3P27 profile across patient tissues and cancer cell-line models. MTCO3P27 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, MTCO3P27 is differentially expressed in 3, with the highest sampling consensus in THCA. Additionally, MTCO3P27 RNA expression shows 4,340 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight KIRC, THCA, and KIRP as cancer lineages where MTCO3P27 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTCO3P27 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTCO3P27 survival associations across molecular data types. MTCO3P27 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTCO3P27 RNA expression–survival associations across cancer types. High MTCO3P27 expression shows unfavorable associations in PAAD, LUSC, UCEC, CESC and ESCA, but favorable associations in KIRC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .002). Together, the overview and detailed table identify KIRC as the clearest survival context for MTCO3P27 RNA expression.
This table summarizes MTCO3P27 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MTCO3P27. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTCO3P27 shows higher tumor expression in THCA, PRAD and LUSC. The THCA box plot shows higher MTCO3P27 RNA expression in tumor versus normal tissue (log2 FC = +0.028, t-test p = .033).
This table shows molecular features associated with MTCO3P27 in patient tissues and cancer cell lines. In patient samples, MTCO3P27 shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set.
