Q-omics provides the consensus-scored MTCO3P15 profile across patient tissues and cancer cell-line models. MTCO3P15 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, MTCO3P15 is differentially expressed in 1, with the highest sampling consensus in BRCA. Additionally, MTCO3P15 RNA expression shows 7,447 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight MESO, BRCA, and GBM as cancer lineages where MTCO3P15 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTCO3P15 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTCO3P15 survival associations across molecular data types. MTCO3P15 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTCO3P15 RNA expression–survival associations across cancer types. High MTCO3P15 expression shows unfavorable associations in MESO, LIHC, BRCA, ACC and STAD, but favorable associations in HNSC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .016). Together, the overview and detailed table identify MESO as the clearest survival context for MTCO3P15 RNA expression.
This table summarizes MTCO3P15 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for MTCO3P15. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTCO3P15 shows higher tumor expression in BRCA. The BRCA box plot shows higher MTCO3P15 RNA expression in tumor versus normal tissue (log2 FC = +0.125, t-test p = .017).
This table shows molecular features associated with MTCO3P15 in patient tissues and cancer cell lines. In patient samples, MTCO3P15 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
