MTCO3P15

Across TCGA pan-cancer cohorts, MTCO3P15 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MTCO3P15 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MTCO3P15 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTCO3P15 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

MESO, LIHC, and HNSC are the cancer types where MTCO3P15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.052	0.528	.016	72	view →
LIHC	DFS	Tertile	II,III,IV	0.092	0.435	<.001	54	view →
HNSC	DFS	Tertile	All	0.594	0.336	.017	45	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
ACC	DFS	Tertile	III,IV	0.010	0.364	<.001	27	view →
STAD	DFS	Median	IV	0.249	0.694	.005	24	view →
PAAD	OS	Tertile	All	0.414	0.628	.013	18	view →
UCS	OS	Tertile	IV	1.000	0.293	.035	18	view →
THCA	OS	Tertile	III,IV	0.741	0.977	.023	18	view →
LGG	DFS	Tertile	All	0.175	0.434	.002	15	view →
THYM	DFS	Tertile	All	0.180	0.738	<.001	12	view →
READ	OS	Tertile	IV	0.289	0.899	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MTCO3P15–MESO (OS)

Open the MESO breakdown →