MTCO2P25

Across TCGA patient cohorts, MTCO2P25 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,118 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTCO2P25-associated GO terms across cancer lineages are Proton transmembrane transport, Regulation of telomere maintenance in response to DNA damage, and Regulation of insulin secretion. Each is linked with MTCO2P25 in more than 7 cancer types. Because this analysis shows association rather than direction, both MTCO2P25-to-partner and partner-to-MTCO2P25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton transmembrane transport grouped by MTCO2P25-low versus MTCO2P25-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCO2P25→partner) and Y-score (partner→MTCO2P25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Proton transmembrane transport →	+0.076	+0.114	<.001	<.001	3	8
ESCA	Regulation of telomere maintenance in response to DNA damage →	+0.082	+0.130	<.001	.002	3	8
ESCA	Regulation of insulin secretion →	+0.045	+0.099	<.001	.002	3	8
STAD	Regulation of endosome size →	+0.067	+0.150	<.001	<.001	3	8
ESCA	Regulation of DNA strand elongation →	+0.089	+0.149	<.001	<.001	3	8
ESCA	Transcription-coupled nucleotide-excision repair →	+0.062	+0.182	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,118 associations by consensus.

Proton transmembrane transport by MTCO2P25 expression — ESCA

Explore this box plot interactively →