MTCO2P25

Across TCGA pan-cancer cohorts, MTCO2P25 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MTCO2P25 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher MTCO2P25 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTCO2P25 expression acts as an unfavorable survival marker.

KICH, LIHC, and PCPG are the cancer types where MTCO2P25 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.070	0.882	<.001	90	view →
LIHC	OS	Tertile	II,III,IV	0.059	0.772	<.001	72	view →
PCPG	OS	Tertile	All	0.516	0.948	.002	33	view →
HNSC	DFS	Tertile	All	0.556	0.722	.010	30	view →
STAD	DFS	Quartile	IV	0.097	0.409	.025	20	view →
SKCM	OS	Tertile	IV	0.179	0.755	<.001	18	view →
UCS	OS	Tertile	All	0.185	0.686	.034	18	view →
DLBC	DFS	Quartile	II,III,IV	0.396	0.853	.033	12	view →
THCA	DFS	Tertile	III,IV	0.158	0.751	.003	12	view →
SARC	OS	Tertile	All	0.241	0.611	.021	6	view →
UCEC	OS	Tertile	All	0.886	0.933	.021	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MTCO2P25–KICH (OS)

Open the KICH breakdown →