MTCO1P22

Across TCGA patient cohorts, MTCO1P22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,627 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTCO1P22-associated GO terms across cancer lineages are Cellular respiration, Proton transmembrane transport, and Electron transport chain. Each is linked with MTCO1P22 in more than 20 cancer types. Because this analysis shows association rather than direction, both MTCO1P22-to-partner and partner-to-MTCO1P22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular respiration grouped by MTCO1P22-low versus MTCO1P22-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCO1P22→partner) and Y-score (partner→MTCO1P22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cellular respiration →	+0.050	+0.620	.007	<.001	2	21
ESCA	Proton transmembrane transport →	+0.035	+0.566	<.001	<.001	3	20
ESCA	Electron transport chain →	+0.068	+0.979	.001	<.001	3	19
ESCA	Respiratory electron transport chain →	+0.076	+0.939	.001	<.001	3	19
ESCA	Mitochondrial electron transport, NADH to ubiquinone →	+0.047	+0.705	<.001	<.001	3	19
ESCA	Aerobic respiration →	+0.056	+0.676	.003	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,627 associations by consensus.

Cellular respiration by MTCO1P22 expression — ESCA

Explore this box plot interactively →