MTCO1P22

Across TCGA pan-cancer cohorts, MTCO1P22 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MTCO1P22’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MTCO1P22 RNA is repressed in tumor relative to normal tissue. In most cancer types MTCO1P22 is over-expressed in tumor, although a few such as KIRC and PAAD show the opposite, repressed pattern.

KIRC, KICH, and PAAD are the cancer types where MTCO1P22 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTCO1P22 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.188	.001	7	view →
KICH	All	All	+0.875	<.001	5	view →
PAAD	Female	All	−0.429	.009	2	view →
CHOL	Male	All	−0.141	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MTCO1P22–KIRC

Open the KIRC breakdown →