Q-omics provides the consensus-scored MTCO1P22 profile across patient tissues and cancer cell-line models. MTCO1P22 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, MTCO1P22 is differentially expressed in 4, with the highest sampling consensus in KIRC. Additionally, MTCO1P22 RNA expression shows 14,753 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and KIRC as cancer lineages where MTCO1P22 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTCO1P22 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTCO1P22 survival associations across molecular data types. MTCO1P22 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTCO1P22 RNA expression–survival associations across cancer types. High MTCO1P22 expression shows unfavorable associations in UCEC and ESCA, but favorable associations in ACC, BLCA, THCA and KICH. The ACC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for MTCO1P22 RNA expression.
This table summarizes MTCO1P22 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MTCO1P22. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTCO1P22 shows lower tumor expression in KIRC, PAAD and CHOL and higher tumor expression in KICH. The KIRC box plot shows higher MTCO1P22 RNA expression in normal versus tumor tissue (log2 FC = −0.188, t-test p = .001).
This table shows molecular features associated with MTCO1P22 in patient tissues and cancer cell lines. In patient samples, MTCO1P22 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
