Across TCGA patient cohorts, MT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,306 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MT4-associated GO terms across cancer lineages are Regulation of odontogenesis of dentin-containing tooth, tRNA 5'-end processing, and Regulation of ubiquitin protein ligase activity. Each is linked with MT4 in more than 6 cancer types. Because this analysis shows association rather than direction, both MT4-to-partner and partner-to-MT4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT4→partner) and Y-score (partner→MT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Regulation of odontogenesis of dentin-containing tooth →	+0.041	+1.547	<.001	<.001	3	7
STAD	tRNA 5'-end processing →	+0.083	+0.295	<.001	<.001	3	6
STAD	Regulation of ubiquitin protein ligase activity →	+0.087	+0.332	<.001	<.001	3	6
STAD	tRNA 3'-end processing →	+0.053	+0.264	<.001	<.001	3	6
STAD	Protein localization to chromatin →	+0.070	+0.522	<.001	<.001	3	6
ESCA	Establishment of skin barrier →	+0.072	+0.414	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,306 associations by consensus.

Exploration

MT4 survival (RNA) · tumor vs normal (RNA) · all MT4 data types