MT4

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MT4 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MT4-associated genes across cancer lineages are Pericytes. Each is linked with MT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MT4-to-partner and partner-to-MT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pericytes grouped by MT4-low versus MT4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT4→partner) and Y-score (partner→MT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPericytes →+0.061+3.113.001.01231
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Pericytes by MT4 expression — UCEC

Box plot of Pericytes in MT4-low vs MT4-high samples in UCEC.

Explore this box plot interactively →

Exploration