MT-TQ

Q-omics provides the consensus-scored MT-TQ profile across patient tissues and cancer cell-line models. MT-TQ expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in BRCA. Additionally, MT-TQ RNA expression shows 1,020 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight BRCA, and KIRP as cancer lineages where MT-TQ shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes MT-TQ survival associations across molecular data types. MT-TQ RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MT-TQ data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	BRCA (108)	view →

This table ranks reproducible MT-TQ RNA expression–survival associations across cancer types. High MT-TQ expression shows unfavorable associations in BRCA, LUAD, OV, LIHC and PRAD. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for MT-TQ RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.165	0.924	<.001	108	view →
LUAD	DFS	Tertile	All	0.206	0.767	.006	45	view →
OV	DFS	Tertile	III,IV	0.252	0.380	.009	42	view →
LIHC	DFS	Tertile	All	0.094	0.526	.017	18	view →
PRAD	OS	Tertile	All	0.790	0.886	.032	6	view →

Pink = unfavorable, green = favorable. all 5 lineages →

MT-TQ-BRCA (OS)

Explore this curve interactively →