Across TCGA patient cohorts, MT-TL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,078 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MT-TL2-associated GO terms across cancer lineages are Proton transmembrane transport, NADH dehydrogenase complex assembly, and Oxidative phosphorylation. Each is linked with MT-TL2 in more than 17 cancer types. Because this analysis shows association rather than direction, both MT-TL2-to-partner and partner-to-MT-TL2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TL2→partner) and Y-score (partner→MT-TL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Proton transmembrane transport →	+0.031	+0.154	.003	<.001	3	18
HNSC	NADH dehydrogenase complex assembly →	+0.030	+0.549	<.001	<.001	3	18
HNSC	Oxidative phosphorylation →	+0.024	+0.501	<.001	<.001	3	17
CHOL	Mitochondrial electron transport, NADH to ubiquinone →	+0.028	+0.955	.001	<.001	3	16
MESO	Methylglyoxal metabolic process →	+0.035	+0.908	.006	.007	1	17
HNSC	ATP synthesis coupled electron transport →	+0.025	+0.447	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,078 associations by consensus.

Exploration

MT-TL2 survival (RNA) · tumor vs normal (RNA) · all MT-TL2 data types